Archive for October, 2010

Recently on KTVU: Study Shows Hormone Therapy Increased Cancer Risk

Thursday, October 28th, 2010

Dr. Ricki Pollycove recently gave advice on the KTVU piece: Study Shows Hormone Therapy Increased Cancer Risk, John Fowler reports. Fowler quotes Dr. Ricki as saying, “this news should not scare women, but empower them. To talk with their doctors to use the right hormones after menopause. That risks, in fact, are very small.”

Knowing All the Facts About the New HRT Study

Friday, October 22nd, 2010

The single largest barrier to women taking ET/HT and allowing themselves to feel better after menopause is the fear of breast cancer.  Informed physicians can’t just sit by and allow the media to get this important story wrong.

The study just released regarding hormone replacement therapy (HRT) and breast cancer released October 20th (from WHI group Chlebowski et al) has been met with fearful reactions by the news media, but what can we learn from this new study? For one thing, the absolute risk is exactly what we knew from before. There is a .008% increase risk for a breast cancer diagnosis with an increase risk of death from breast cancer of a .012%. These are very tiny individual risks. 

The new information is in the details of breast cancer cell types associated with Medroxyprogesterone Acetate (MPA, the progestin found in Prempro), and the incidence of higher death rates. The problem remains with MPA. The estrogen alone trial of the WHI study showed a 23% decreased risk if being diagnosed with breast cancer.

As of today we even have very reassuring data about estradiol and natural progesterone not statistically increasing risk for breast cancer and also showing much better survival if one does get a breast cancer diagnosis if the woman is on estradiol at the time of diagnosis. The detail of which hormones a woman takes is very important. We must help make women aware of news about different products that does not relate to their risk status, unless they choose to be on Prempro for 11+ years.

I have never given any age of a woman a Premarin or PremPro prescription for a new start of hormone replacement therapy for the management of menopausal symptoms. There are many better options and that is the bottom line for this article as well. Simply look at transdermal estrogens, all biologically identical to that which we naturally make in our bodies and for which nature selected over millions of “randomized blinded trial years” (the process of natural selection at its finest in my opinion). In all sorts of research, at cellular levels, as well as gene regulation and gene suppressions/expression studies, estradiol is very positive in its effects on cell differentiation; in essence, keeping healthy breast cells healthy. That is the goal of ideal hormone support for every tissue we study: the enhancement of balanced regulated cell growth and positive anti-oxidant effects of estradiol.

Women’s Health Day

Tuesday, October 5th, 2010

Come down to the 450 Sutter Pharmacy on October 19th for a discussion with Dr. Ricki Pollycove on making the best choices in Menopause, Fact vs. Fiction and what You need to know. You’ll also have the opportunity to purchase her latest book, The Pocket Guide to BioIdenitcal Hormones.

October 19th, 2010 – 5:30p to 7:00p

450 Sutter Pharmacy

450 Sutter St, 7th Floor
San Francisco, CA (map)

Please RSVP by October 18th to Elaine Chan, 415-392-4137, as space is limited.
Hors d’oeuvres, Drinks and Prizes will be provided.
$10/person donation (100% of proceeds will go to Sofia Project)

Sophia Project serves children and families who are at risk of recurring homelessness and its effects. They are located in a low income neighborhood in West Oakland. Their programs include infant and toddler program and care, early childhood education, extended hours of childcare, a before and after school program which includes both tutoring and care, artistic activities, a weekend respite program, parenting education and family support services. Working with the children and mothers in this way enhances a healthy family life and creates a firm foundation of early learning, critical to later success in school.